Randomized & comparative effectiveness trials

Head-to-head and placebo-controlled trials testing treatments for hypertension, heart failure and related conditions.

Completed
Comparison of Three Anti-Hypertensive Combination Therapies in Black Patients, conducted in 10 sites in 6 sub-Saharan African countries (Cameroon, Kenya, Mozambique, Nigeria, South Africa and Uganda)
Completed
The Investigation of the Management of Pericarditis (IMPI) Trial
Completed
Bi treatment with hydralazine/nitrates vs placebo in Africans admitted with acute Heart Failure (BA-HEF)
Completed
Evaluation of a triple single-pill combination (triple pill)-based treatment protocol compared to the Nigeria hypertension treatment protocol for improving BP control in Nigeria (VERONICA Trial)
Completed
GMRx2-PCT trial
VERONICA Trial: Extension
Planning
ACTION Study: trial of potassium-enriched salt on top of GMRx2, to test the effect on potassium levels
Planning
VERONICA-Amiloride: trial of the effect of amiloride on top of GMRx2 on potassium levels